J Indian Soc Pedod Prev Dent. 2017
Jul-Sep;35(3):229-237. doi: 10.4103/JISPPD.JISPPD_242_16.
A comparative
evaluation of the remineralization potential of three commercially available
remineralizing agents on white spot lesions in primary teeth: An in vitro
study.
영구치의 화이트스폿리전(초기충치)에 상업적으로 이용가능한 3가지 재광화촉진재의 치아재광화효과비교평가
Kamath P1, Nayak R1, Kamath SU2, Pai D1.
Author
information
1
Department of Pedodontics and
Preventive Dentistry, Manipal College of Dental Sciences Manipal, Manipal
University, Manipal, Karnataka, India.
2
Department of Biochemistry, KMC
Manipal, Manipal University, Manipal, Karnataka, India.
Abstract
BACKGROUND:
The focus
in caries management has shifted to early detection of caries lesions and
targeted noninvasive management of incipient lesions using novel remineralizing
agents.
AIM:
This
study aimed to compare and evaluate the remineralization potential of commercially
available agents containing nano-hydroxyapatite (nano-HA), casein
phosphopeptide-amorphous calcium phosphate fluoride (CPP-ACPF), and Tricalcium
phosphate (TCP) on artificially induced white spot lesions in primary teeth.
SETTINGS AND
DESIGN:
This is
an in vitro double-blind randomized study.
MATERIALS AND
METHODS:
Forty
extracted or exfoliated primary teeth were selected and randomized as follows:
Group I: FTCP, Group II: fluoridated dentifrice, Group III: CPP-ACPF, and Group
IV: Nano-HA. DIAGNOdent readings and scanning electron microscope (SEM) energy
dispersive X-ray (EDX) analysis were carried out at baseline. The samples were
subjected to the test agents after inducing white spot lesions. The readings
were repeated postdemineralization and postremineralization.
STATISTICAL
ANALYSIS:
The data
were analyzed using IBM SPSS version 20 software with one-way ANOVA, post hoc
Tukey's HSD, and paired t-test.
RESULTS:
SEM
evaluation showed favorable surface changes in all the four study groups after
remineralization therapy. Intragroup comparison of DIAGNOdent and EDX readings
showed a highly significant difference between baseline, postdemineralization,
and postremineralization values. However, the intergroup comparison was
statistically nonsignificant.
CONCLUSION:
All test
agents were comparable in their remineralization potential.
세가지 물질 모두 치아재광화 능력이 있다.
J
Contemp Dent Pract. 2016 Mar 1;17(3):192-7.
An in situ Evaluation
of Bioactives on the Morphology of Bleached Enamel.
미백처리된 에나멜의 표면 변화에 바이오엑티브한 물질의 평가
da Rosa Nogueira T1, Alexandrino LD1, de Lima Gomes Ydo S1, de Melo Alencar C1, Alves EB1, Silva CM2.
Author
information
1
Department of Restorative
Dentistry, Federal University of Pará, Para, Brazil.
2
Professor, Department of
Restorative Dentistry, Federal University of Pará, Augusto Correa Street no. 1,
Guamá, Belém, Pa, CEP: 66075110, Brazil, Phone: +559132521269, e-mail:
cecymsilva@gmail.com.
Abstract
AIM:
The aim
of this study was to use surface rugosity analysis (Ra) and scanning electron
microscopy (SEM) comparing effects of nano-hydroxyapatite (NANO), casein
phosphopeptide-amorphous calcium phosphate (CPP-ACP), and NovaMin (NOVA) on
enamel's human morphology bleached with 37.5% hydrogen peroxide.
MATERIALS AND
METHODS:
Forty
specimens (3 × 3 × 3 mm) were obtained from fully included third molars and
four specimens were attached in the first molars of the volunteers. The
POLA-positive control has only been bleached. Three experimental groups were
bleached and treated with respective bioactive: NANO, CPP-ACP, and NovaMin. The
Ra analyses were performed before and after the treatment using a rugosimeter.
The obtained photomicrographs were analyzed using SEM (n = 3) by three
examiners, and the study was double blind.
RESULTS:
The Ra
results were analyzed by one-way analysis of variance and Tukey's post hoc test
(p < 0.05). All experimental groups showed significant differences of the
others; however, the experimental groups were not significantly different from
each other.
CONCLUSION:
The
enamel morphology of the bioactive-treated groups had more regular surfaces,
than the others.
바이오엑티브한 물질로 처리 된 그룹의 에나멜 표면이 다른 그룹보다 일률적이었다.
KEYWORDS:
Bioactive
agents; NANO-P; Rugosity analysis; Scanning electron microscopy.
Am J Dent.
2015 Feb;28(1):51-6.
An in vitro
evaluation of the effect of fluoride products on white spot lesion remineralization.
화이트스폿 리전(초기충치)에 불소제품이 미치는 효과 평가
Mielczarek A, Gedrange T, Michalik J.
Abstract
PURPOSE:
To compare the effect of
combinations of fluoride (F) products on remineralization of caries-like
lesions.
METHODS:
Demineralized human enamel
specimens were assessed by surface microhardness (SMH), stratified and
allocated to five treatments groups: (1) Toothpaste containing 1% nano
hydroxyapatite (HAP) + 1,450 ppm F; (2) Tooth mousse containing 10% casein
phosphopeptide-amorphous calcium phosphate (CPP-ACP) + 900 ppm F plus F
toothpaste (1,450 ppm F as NaF); (3) F varnish containing 22,600 ppm F plus F
toothpaste (1,450 ppm F as NaF); (4) F toothpaste (1,450 ppm F as NaF); and (5)
placebo--distilled water (P). Each group was treated in a 21-day pH-cycling
model. Groups 1, 4 and 5 were treated 2x/day. In Group 3, the tooth mousse was
administered 1x/day plus 2x/day F toothpaste treatment. In Group 4, F varnish
was administered 1x/week plus 2x/day treatment with F toothpaste. After
cycling, SMH was re-measured and cross-sectional microhardness measurements
were taken.
RESULTS:
Groups 1-4 produced significant
rehardening of enamel. In the superficial layer (25-5ㅏ0 μm deep) significantly
higher mineralization (up to 83%, by Volume (V), P < 0.0001) was achieved
for Groups 2 and 3. In the area of 75-100 μm deep, the highest mineralization
was observed for Groups 1 and 4 (V% = 68-83%).
나노 하이드록시아파타이트가 들어간 그룹의 재광화효과가 가장 뛰어났다.
Zhonghua Kou Qiang Yi Xue Za Zhi. 2009
May;44(5):297-300.
[The preparation
of nano-hydroxyapatite and preliminary observation on its effects on the
occlusion of dentinal tubule].
나노하이드록시아파타이트의 상아세관 봉쇄 효과
[Article in Chinese]
Wang ZJ1, Sa Y, Ma X, Wang YN, Jiang T.
Author
information
1
Key Laboratory for Oral
Biomedical Engineering of Ministry of Education, School of Stomatology, Wuhan
University, Wuhan 430079, China.
Abstract
OBJECTIVE:
To
synthesize nano-hydroxyapatite (nano-HA) and evaluate its effect on the
occlusion of dentinal tubules in vitro, and therefore provide evidence for the
clinical application.
METHODS:
(NH(4))(2)HPO(4)
and Ca(NO3)2 were used to form nano-HA, which was characterized by scanning
electron microscopy (SEM), transmission electron microscopy (TEM), Fourier
transform infrared spectrometer (FTIR) and X-ray diffractometer (XRD)
respectively. Twenty-four dentin slabs were obtained from 8 healthy third
molars and randomly divided into 3 groups, which were control group, casein
phosphopeptide-amorphous calcium phosphate (CPP-ACP) group, and nano-HA group.
After the CPP-ACP and nano-HA were topically applied to the slabs of two study
groups twice a day for 7 days, the surface of slab dentin was observed using
SEM.
RESULTS:
SEM, TEM,
FTIR, and XRD tests showed that nano-HA was synthesized successfully. SEM
observations revealed that the sealing of dentinal tubules of nano-HA group was
extremely high when compared with those of control and CPP-ACP group.
CONCLUSIONS:
In
comparison with CPP-ACP, nano-HA could occlude dentinal tubules more
effectively in vitro.
CPP-ACP에 비해 나노하이드록시아파타이트가 상아세관을 보다 효과적으로 봉쇄할 수 있다.
