subject | 2019년 나노생체공학학회지에 올라온 나노하이드록시아파타이트의 에나멜재광화논문~ |
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writer | 관리자 |
date | 19-09-27 16:06 |
hit | 1,239 |
관련링크본문J Nanobiotechnology. 2019 Jan 25;17(1):17. doi: 10.1186/s12951-019-0454-6. Enamel remineralization and repair results of Biomimetic Hydroxyapatite toothpaste on deciduous teeth: an effective option to fluoride toothpaste.Bossù M1, Saccucci M2, Salucci A1, Di Giorgio G1, Bruni E3, Uccelletti D3, Sarto MS4, Familiari G5, Relucenti M5, Polimeni A1. Author information
AbstractBACKGROUND:Dental caries is a recognized worldwide public health problem. Despite being one of the most effective strategies against dental caries, the excessive use of fluorine may result in a potential risk of developing dental fluorosis especially in children under age of six. The purpose of this work is to analyze a fluorine-free toothpaste containing Biomimetic Hydroxyapatite to assess enamel re-mineralizing and repairing properties. RESULTS:The study was performed in vitro and in vivo, comparing the hydroxyapatite toothpaste with two others toothpaste containing different fluorine concentrations. The coating effect of the micro-structured Hydroxyapatite nanoparticles reintegrates the enamel with a biomimetic film reproducing the structure and the morphology of the biologic Hydroxyapatite of the enamel. As demonstrated, the coating is due to the deposit of a new layer of apatite, which presents fewer particles than the natural enamel, not based on the chemical-physical changes occurring in fluorinated toothpastes. Moreover, it shows resistance to brushing as a consequence of chemical bonds between the synthetic and natural crystals of the enamel. CONCLUSIONS:The use of Biomimetic Hydroxyapatite toothpastes has proven to be a valuable prevention measure against dental caries in primary dentition since it prevents the risk of fluorosis. 생체모방 하이드록시아파타이트가 영구치 충치예방에 유효한 수단이다.(치아불소증이 생길 염려도 없다) KEYWORDS:Biomimetic nanocrystals; Carbonate-hydroxyapatite; Enamel remineralization toothpaste; Zn-carbonate hydroxyapatite |
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