subject 재미난 연구: nano hydroxyapatite, bioactive glass, 불소(NaF) : 재광화효과
writer 관리자
email
date 19-10-01 13:49
hit 1,736

본문

The Remineralizing Potential of Nano Bioactive Glass Versus Nanohydroxyapatite on Dentine as Affected by PH Cycling

Article 2, Volume 5, Issue 4, Autumn 2018, Page 327-334  XML PDF (754.64 K)
Document Type: Original Article
DOI: 10.21608/adjg.2018.20017
Authors
Dalia M. Elasser1; Maha A. Niazy2; Doaa A.E Elsharkawy3; Mai Sh Mansour4
1Demonstrator, operative dentistry Department, Faculty of Dental Medicine for Girls, Al-Azhar University, Egypt.
2Professor and Head of operative dentistry Department, Faculty of Dental Medicine for Girls, Al -Azhar University, Egypt.
3Lecturer of Operative Dentistry Department, Faculty of Dental Medicine for Girls, Al-Azhar University, Egypt
4Associate Professor, Oral Medicine Department, Faculty of Dental Medicine for Girls, Al-Azhar University, Egypt.
Abstract

Objective: The aim of this study was to evaluate the remineralizing potential of nano bioactive glass (BG) in comparison with nano hydroxy appetite (HA) incorporated into adhesive on demineralized dentine as affected by PH cycling.
Materials and Methods: sixty sound premolars were extracted for orthodontic treatment. Class I Cavities were prepared in premolars with a depth 3mm. The specimens were divided into three treatment groups including 20%BG incorporated into self-etch adhesive (3M ESPE), 20% HA incorporated also into self-etch adhesive, and gel of sodium fluoride NaF was used as a positive control. 37% phosphoric acid was applied for each cavity for lesion creation. Modified adhesive and composite restoration were applied according to the manufacture instructions. An in vitro pH cycling model was used to mimic oral cavity condition through treatment solutions, acidic buffer (4 hours ) and neutral buffer(20 hours) for 30 days. The specimens were evaluated for radiodensity using Digital Radiographic (DBSW software) and Environmental Scanning Electron Microscope (ESEM) at different stages of the study (before demineralization, after demineralization and after remineralization). The significance level was set at p ≤0.05. Results: all groups showed significant reminerlization. Groups with BG nanoparticles and HA nanorods showed a higher increase in the radiodensty of demineralized dentine than NaF group. BG group showed higher results under neutral condition.

 

바이오엑티브 글래스 그룹과 나노 하이드록시아파타이트 그룹이 불소(NaF)보다 탈회된 상아질을 재광화 하는 효과가 뛰어났다.


Conclusion: BG and HA modified adhesives may be valuable tools to enhance remineralization of affected dentin. 

Keywords
Affected dentin; Bioactive glass; Hydroxyapatite; Remineralization; Fluoride; Nanoparticles
Main Subjects
Operative Dentistry
References
Ngo HC, Mount G, Mc Intyre J, Tuisuva J, Von Doussa RJ. Chemical exchange between glass-ionomer restorations and residual carious dentine in permanent molars: an in vivo study. J dent. 2004;34608-13.
2.
Yoshiyama M, Doi J, Nishitani Y, Itota T, Tay F, Carvalho R, Pashley D. Bonding ability of adhesive resins to caries affected and caries infected dentin. J Appl oral Sci 2004: 12:171- 6.
3.
Conrado C A. Remineralization of carious dentine: In vitro microradiographic study in human teeth capped by calcium hydroxide. Braz Dent J 2004: 15: 59- 62.
4.
Besinis A, van Noort R, MartinN. Infiltration of demineralized dentin with silica and hydroxyapatite nanoparticles. Dent Mater.2012;28:1012-23.
5.
Prabhakar AR, Arali V. Fluoride and bioactive glass using bioerodible gel systems. J Dent Res Dent Clinic Dent Prospects 2009;3:117-21.
6.
Mishra P, Palamara JE, Tyas MJ, Burrow MF. Effect of loading and pH on the subsurface demineralization of dentin beams. Calci Tis Intern. 2006;79:273-7.
7.
Yamaguchi K, Miyazaki M, Takamizawa T, Inage H, Moore BK. Effect of CPP–ACP paste on mechanical properties of bovine enamel as determined by an ultrasonic device. J Dent. 2006;34:230-6.
8.
Cao CY, Mei ML, Li QL, Lo EC, Chu CH. Methods for biomimetic remineralization of human dentine: a systematic review. Inter J molecul Sci. 2015;16:4615-27.
9.
Nunes MF, Swift EJ, Perdigao J. Effects of adhesive composition on microtensile bond strength to human dentin. Amer J Dent. 2001;14:340-3.
10.
www.physiologyweb.com/calculators/percent_solutions_calculator.html.
11.
Prabhakar AR, Manojkumar AJ, Basappa N. In vitro remineralization of enamel subsurface lesions and assessment of dentine tubule occlusion from NaF dentifrices with and without calcium. J Ind Soci Pedo Prev Dent. 2013;31:29-35.
12.
Bali P, Prabhakar A R and Basappa N. Invitro comparative evaluation of compressive strength and antibacterial activity of conventional GIC and hydroxyapatite reinforced GIC in different storage media .J Clinic Diag Res 2015; 9:51-55.
13.
Nucã C., Bocskay T., Amariei C. and Rusu L. Study regarding the histological features of enamel caries. Oral H & Dent Manag Black Sea Countr. 2005; 4: 5-12.

 

Mehdawi I, Abou Neel EA, Valappil SP,Palmer G, Salih V, Pratten J, Spratt DA, Young AM. Development of remineralizing,antibacterial dental materials. Acta Biomater. 2009; 5: 2525-39.
15.
Mahmoud N, Riad M, Farag A. Remineralizing potential of hydroxyapatite and fluoride nanoparticles on dentin. Egypt dent J. 2015;61:1872.
16.
Featherstone JD, Doméjean S. The role of remineralizing and anticaries agents in caries management. Adv Dent Res 2012;24:28-31.
17.
Hannig M, Hannig C. Nanotechnology and its role in caries therapy. Adv Dent Res 2012;24:53-7.
18.
Khvostenko D, Hilton TJ, Ferracane JL, Mitchell JC, Kruzic JJ. Bioactive glass fillers reduce bacterial penetration into marginal gaps for composite restorations. Dent Mater. 2016;32:73-81.
19.
Haghgoo R, Ahmadvand M, Moshaverinia S. Remineralizing Effect of Topical NovaMin and Nano-hydroxyapatite on caries-like Lesions in Primary teeth. J Dent Pract. 2016;17:645-9.
20.
Pereira J, Martineli A,Tung M. Replica of human dentin treated with different desensitizing agents. A methodological SEM study in vitro. Braz Dent J.2002;13(2):75-85. 21 Tschoppe P, Zandim DL, Martus P, Kielbassa AM.Enamel and dentine remineralization by nano-hydroxyapatite toothpastes. J Dent.2011; 430-7.
21.
Wang Z, Jiang T, Sauro S, Wang Y, Thompson I, Watson TF, Sa Y, Xing W, Shen Y, Haapasalo M. Dentine remineralization induced by two bioactive glasses developed for air abrasionpurposes.JDent.2011; 39:746-5

 

sns Link parsing error
  • 페이스북으로 보내기
  • 트위터로 보내기
  • 구글플러스로 보내기
  • 블로그 보내기
  • 텔레그램 보내기

댓글목록

등록된 댓글이 없습니다.

이전글 다음글