subject 재미난 연구: nano hydroxyapatite, bioactive glass, 불소(NaF) : 재광화효과
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date 19-10-01 13:49
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The Remineralizing Potential of Nano Bioactive Glass Versus Nanohydroxyapatite on Dentine as Affected by PH Cycling

Article 2, Volume 5, Issue 4, Autumn 2018, Page 327-334  XML PDF (754.64 K)
Document Type: Original Article
DOI: 10.21608/adjg.2018.20017
Authors
Dalia M. Elasser1; Maha A. Niazy2; Doaa A.E Elsharkawy3; Mai Sh Mansour4
1Demonstrator, operative dentistry Department, Faculty of Dental Medicine for Girls, Al-Azhar University, Egypt.
2Professor and Head of operative dentistry Department, Faculty of Dental Medicine for Girls, Al -Azhar University, Egypt.
3Lecturer of Operative Dentistry Department, Faculty of Dental Medicine for Girls, Al-Azhar University, Egypt
4Associate Professor, Oral Medicine Department, Faculty of Dental Medicine for Girls, Al-Azhar University, Egypt.
Abstract

Objective: The aim of this study was to evaluate the remineralizing potential of nano bioactive glass (BG) in comparison with nano hydroxy appetite (HA) incorporated into adhesive on demineralized dentine as affected by PH cycling.
Materials and Methods: sixty sound premolars were extracted for orthodontic treatment. Class I Cavities were prepared in premolars with a depth 3mm. The specimens were divided into three treatment groups including 20%BG incorporated into self-etch adhesive (3M ESPE), 20% HA incorporated also into self-etch adhesive, and gel of sodium fluoride NaF was used as a positive control. 37% phosphoric acid was applied for each cavity for lesion creation. Modified adhesive and composite restoration were applied according to the manufacture instructions. An in vitro pH cycling model was used to mimic oral cavity condition through treatment solutions, acidic buffer (4 hours ) and neutral buffer(20 hours) for 30 days. The specimens were evaluated for radiodensity using Digital Radiographic (DBSW software) and Environmental Scanning Electron Microscope (ESEM) at different stages of the study (before demineralization, after demineralization and after remineralization). The significance level was set at p ≤0.05. Results: all groups showed significant reminerlization. Groups with BG nanoparticles and HA nanorods showed a higher increase in the radiodensty of demineralized dentine than NaF group. BG group showed higher results under neutral condition.

 

바이오엑티브 글래스 그룹과 나노 하이드록시아파타이트 그룹이 불소(NaF)보다 탈회된 상아질을 재광화 하는 효과가 뛰어났다.


Conclusion: BG and HA modified adhesives may be valuable tools to enhance remineralization of affected dentin. 

Keywords
Affected dentin; Bioactive glass; Hydroxyapatite; Remineralization; Fluoride; Nanoparticles
Main Subjects
Operative Dentistry
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